Article
Epigenomics, Pharmacoepigenomics, and Personalized Medicine in Cervical Cancer.
Public health genomics - 1 Jan 2017
Kabekkodu Shama Prasada, Chakrabarty Sanjiban, Ghosh Supriti, Brand Angela, Satyamoorthy Kapaettu
Abstract excerpt
Epigenomics encompasses the study of genome-wide changes in DNA methylation, histone modifications and noncoding RNAs leading to altered transcription, chromatin structure, and posttranscription RNA processing, respectively, resulting in an altered rate of gene expression. The role of epigenetic modifications facilitating human diseases is well established. Previous studies have identified histone and cytosine...
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