Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Brain enhancer activities at the gene-poor 5p14.1 autism-associated locus.

Scientific reports - 9 Aug 2016

Inoue Yukiko U, Inoue Takayoshi

Abstract excerpt

Due to the vast clinical and genetic heterogeneity, identification of causal genetic determinants for autism spectrum disorder (ASD) has proven to be complex. Whereas several dozen 'rare' genetic variants for ASD susceptibility have been identified, studies are still underpowered to analyse 'common' variants for their subtle effects. A recent application of genome-wide association studies (GWAS) to ASD indicated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autistic Disorder
Share to Chromosomes, Artificial, Bacterial
Share to Chromosomes, Human, Pair 5

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Techniques

Share to Microfilament Proteins

Share to Oligonucleotides, Antisense

Share to Regulatory Sequences, Nucleic Acid

Share to RNA, Long Noncoding

Source

Open in PubMed Open full text

Identifiers

PMID: 27503586
DOI: 10.1038/srep31227
PMCID: PMC4977510

Genes

CDH10
CDH9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Brain enhancer activities at the gene-poor 5p14.1 autism-associated locus.PMID 27503586Read ↗

Bridging between mouse and human enhancer-promoter long-range interactions in neural stem cells, to understand enhancer function in neurodevelopmental diseaseSemantic proximity Read ↗

A noncoding RNA antisense to moesin at 5p14.1 in autism.Semantic proximity Read ↗

An atlas of gene regulatory elements in adult mouse cerebrum.Semantic proximity Read ↗

An Atlas of Gene Regulatory Elements in Adult Mouse CerebrumSemantic proximity Read ↗

Conceptualizing Epigenetics and the Environmental Landscape of Autism Spectrum Disorders.Semantic proximity Read ↗

Epigenetics and the Environmental Landscape of Autism Spectrum DisordersSemantic proximity Read ↗

An Adnp frameshift variant disrupts Wnt signalling inducing chromatocytoskeletal defects and autism-related behaviour in male mice.Semantic proximity Read ↗

Transcriptional Gene Silencing of the Autism-Associated Long Noncoding RNA MSNP1AS in Human Neural Progenitor Cells.Semantic proximity Read ↗

Transcriptional consequences of MBD5 disruption in mouse brain and CRISPR-derived neurons.Semantic proximity Read ↗

An eQTL mapping approach reveals that rare variants in the SEMA5A regulatory network impact autism risk.Semantic proximity Read ↗

Parkinson-associated <i>SNCA</i> enhancer variants revealed by open chromatin in mouse dopamine neuronsSemantic proximity Read ↗

Spatio-molecular domains identified in the mouse subthalamic nucleus and neighboring glutamatergic and GABAergic brain structuresSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.