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Article

Molecular and Functional Characterization of Cynomolgus Monkey IgG Subclasses

4 Dec 2010

Abstract excerpt

Studies for vaccine and human therapeutic Ab development in cynomolgus monkeys (cynos) are influenced by immune responses, with Ab responses playing a significant role in efficacy and immunogenicity. Understanding the nature of cyno humoral immune responses and characterizing the predominant cyno IgG types produced and the Fc-FcγR interactions could provide insight into the immunomodulatory effects of vaccines....

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PMID: 21131427
DOI: 10.4049/jimmunol.1001685

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