Article
The 95ΔG mutation in the 5'untranslated region of the norA gene increases efflux activity in Staphylococcus epidermidis isolates.
Microbial pathogenesis - 1 Feb 2017
García-Gómez Elizabeth, Jaso-Vera Marcos E, Juárez-Verdayes Marco A, Alcántar-Curiel María D, Zenteno Juan C, Betanzos-Cabrera Gabriel, Peralta Humberto, Rodríguez-Martínez Sandra, Cancino-Díaz Mario E, Jan-Roblero Janet, Cancino-Diaz Juan C
Abstract excerpt
In the Staphylococcus aureus ATCC25923 strain, the flqB mutation in the 5'untranslated region (5'UTR) of the norA gene causes increased norA mRNA expression and high efflux activity (HEA). The involvement of the norA gene 5'UTR in HEA has not been explored in S. epidermidis; therefore, we examined the function of this region in S. epidermidis clinical isolates. The selection of isolates with HEA was performed...
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