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Article

PCSK9 and lipoprotein (a) levels are two predictors of coronary artery calcification in asymptomatic patients with familial hypercholesterolemia.

Atherosclerosis - 1 Nov 2016

Alonso Rodrigo, Mata Pedro, Muñiz Ovidio, Fuentes-Jimenez Francisco, Díaz Jose Luis, Zambón Daniel, Tomás Marta, Martin Cesar, Moyon Thomas, Croyal Mikaël, Thedrez Aurélie, Lambert Gilles

Abstract excerpt

BACKGROUND AND AIMS: We aimed to assess whether elevated PCSK9 and lipoprotein (a) [Lp(a)] levels associate with coronary artery calcification (CAC), a good marker of atherosclerosis burden, in asymptomatic familial hypercholesterolemia. METHODS: We selected 161 molecularly defined FH patients treated with stable doses of statins for more than a year. CAC was measured using the Agatston method and quantified as...

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Source

Identifiers

PMID: 27594539
DOI: 10.1016/j.atherosclerosis.2016.08.038

Genes

PCSK9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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