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Article

Accelerated subclinical coronary atherosclerosis in patients with familial hypercholesterolemia.

Atherosclerosis - 1 Dec 2011

Neefjes Lisan A, Ten Kate Gert-Jan R, Alexia Rossi, Nieman Koen, Galema-Boers Annette J, Langendonk Janneke G, Weustink Annick C, Mollet Nico R, Sijbrands Eric J, Krestin Gabriel P, de Feyter Pim J

Abstract excerpt

OBJECTIVES: We determined the extent, severity, distribution and type of coronary plaques in cardiac asymptomatic patients with familial hypercholesterolemia (FH) using computed tomography (CT). BACKGROUND: FH patients have accelerated progression of coronary artery disease (CAD) with earlier major adverse cardiac events. Non-invasive CT coronary angiography (CTCA) allows assessing the coronary plaque burden in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydroxymethylglutaryl-CoA Reductase Inhibitors

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Share to Plaque, Atherosclerotic

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Source

Identifiers

PMID: 22018443
DOI: 10.1016/j.atherosclerosis.2011.09.052

Genes

CAD

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