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The Arabidopsis THO/TREX component TEX1 functionally interacts with MOS11 and modulates mRNA export and alternative splicing events.

Plant molecular biology - 1 Feb 2017

Sørensen Brian B, Ehrnsberger Hans F, Esposito Silvia, Pfab Alexander, Bruckmann Astrid, Hauptmann Judith, Meister Gunter, Merkl Rainer, Schubert Thomas, Längst Gernot, Melzer Michael, Grasser Marion, Grasser Klaus D

Abstract excerpt

KEY MESSAGE: We identify proteins that associate with the THO core complex, and show that the TEX1 and MOS11 components functionally interact, affecting mRNA export and splicing as well as plant development. TREX (TRanscription-EXport) is a multiprotein complex that plays a central role in the coordination of synthesis, processing and nuclear export of mRNAs. Using targeted proteomics, we identified proteins that...

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PMID: 28004241
DOI: 10.1007/s11103-016-0561-9

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