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LncRNA MALAT1 promotes development of mantle cell lymphoma by associating with EZH2

1 Dec 2016

Abstract excerpt

BACKGROUND: Mantle cell lymphoma (MCL) is considered an aggressive subtype of non-Hodgkin's lymphoma with variable treatment responses. There is an urgent need to identify novel markers with prognostic and therapeutic value for MCL. Long non-coding RNAs (lncRNAs) have emerged as key regulators in cancers, including MCL. Metastasis-associated lung adenocarcinoma transcript 1(MALAT1), a lncRNA located at...

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PMID: 27998273
DOI: 10.1186/s12967-016-1100-9

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