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Article

Beta2-adrenergic receptor homodimers: Role of transmembrane domain 1 and helix 8 in dimerization and cell surface expression.

Biochimica et biophysica acta. Biomembranes - 1 Sept 2017

Parmar Vikas K, Grinde Ellinor, Mazurkiewicz Joseph E, Herrick-Davis Katharine

Abstract excerpt

Even though there are hundreds of reports in the published literature supporting the hypothesis that G protein-coupled receptors (GPCR) form and function as dimers this remains a highly controversial area of research and mechanisms governing homodimer formation are poorly understood. Crystal structures revealing homodimers have been reported for many different GPCR. For adrenergic receptors, a potential dimer...

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Identifiers

PMID: 27993566
DOI: 10.1016/j.bbamem.2016.12.007
PMCID: PMC5474359

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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