Article
Trough concentration and ABCG2 polymorphism are better to predict imatinib response in chronic myeloid leukemia: a meta-analysis.
Pharmacogenomics - 1 Jan 2017
Jiang Zhi-Ping, Zhao Xie-Lan, Takahashi Naoto, Angelini Sabrina, Dubashi Biswajit, Sun Li, Xu Ping
Abstract excerpt
AIM: The present study aimed to conduct a series of meta-analyses to investigate the influence of imatinib trough concentration (C0), as well as ABCB1 and ABCG2 polymorphisms, on the clinical response in patients with chronic myeloid leukemia (CML). METHODS: A literature search was conducted using the PubMed and Cochrane electronic databases to locate relevant papers from 2003 onward. Then, an initial...
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