Article
Heritability of the shape of subcortical brain structures in the general population.
Nature communications - 15 Dec 2016
Roshchupkin Gennady V, Gutman Boris A, Vernooij Meike W, Jahanshad Neda, Martin Nicholas G, Hofman Albert, McMahon Katie L, van der Lee Sven J, van Duijn Cornelia M, de Zubicaray Greig I, Uitterlinden André G, Wright Margaret J, Niessen Wiro J, Thompson Paul M, Ikram M Arfan, Adams Hieab H H
Abstract excerpt
The volumes of subcortical brain structures are highly heritable, but genetic underpinnings of their shape remain relatively obscure. Here we determine the relative contribution of genetic factors to individual variation in the shape of seven bilateral subcortical structures: the nucleus accumbens, amygdala, caudate, hippocampus, pallidum, putamen and thalamus. In 3,686 unrelated individuals aged between 45 and...
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