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Article

Lifestyle Risk Factors for Breast Cancer in BRCA1/2-Mutation Carriers Around Childbearing Age.

Journal of genetic counseling - 1 Aug 2017

van Erkelens A, Derks L, Sie A S, Egbers L, Woldringh G, Prins J B, Manders P, Hoogerbrugge N

Abstract excerpt

BRCA1/2-mutation carriers are at high risk of breast cancer (BC) and ovarian cancer. Physical inactivity, overweight (body mass index ≥25, BMI), smoking, and alcohol consumption are jointly responsible for about 1 in 4 postmenopausal BC cases in the general population. Limited evidence suggests physical activity also increases BC risk in BRCA1/2-mutation carriers. Women who have children often reduce physical...

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Identifiers

PMID: 27966054
DOI: 10.1007/s10897-016-0049-4
PMCID: PMC5502067

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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