Article
Impact of lifestyle factors on preneoplastic changes in prophylactic oophorectomies of BRCA mutation carriers.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Mar 2012
Primas Helga, Kroiss Regina, Kalteis Karin, Rappaport Christine, Muhr Daniela, Primas Christian, Kubista Ernst, Horvat Reinhard, Oefner Peter, Singer Christian, Wagner And The Austrian Hereditary Breast And Ovarian Cancer Group Teresa
Abstract excerpt
BRCA mutation carriers are at high risk of developing ovarian cancer. Ovarian malignancies are usually identified at an advanced stage with poor prognosis, attributed to inadequate options of early detection. Because of its risk-reducing effect of nearly 96%, prophylactic salpingo-oophorectomy is still the leading option for risk-reduction in women with a positive BRCA mutation status. The presence of ovarian...
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