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Smoking and physical inactivity increase cancer prevalence in BRCA-1 and BRCA-2 mutation carriers: results from a retrospective observational analysis.

Archives of gynecology and obstetrics - 1 Dec 2017

Grill Sabine, Yahiaoui-Doktor Maryam, Dukatz Ricarda, Lammert Jacqueline, Ullrich Mirjam, Engel Christoph, Pfeifer Katharina, Basrai Maryam, Siniatchkin Michael, Schmidt Thorsten, Weisser Burkhard, Rhiem Kerstin, Ditsch Nina, Schmutzler Rita, Bischoff Stephan C, Halle Martin, Kiechle Marion

Abstract excerpt

BACKGROUND: The aim of this analysis in a pilot study population was to investigate whether we can verify seemingly harmful lifestyle factors such as nicotine and alcohol indulgence, obesity, and physical inactivity, as well as a low socioeconomic status for increased cancer prevalence in a cohort of BRCA 1 and 2 mutation carriers. METHODS: The analysis data are derived from 68 participants of the lifestyle...

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Identifiers

PMID: 28975393
DOI: 10.1007/s00404-017-4546-y

Genes

BRCA1
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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