Article
Differential Radiographic Appearance of BRAF V600E-Mutant Metastatic Colorectal Cancer in Patients Matched by Primary Tumor Location.
Journal of the National Comprehensive Cancer Network : JNCCN - 1 Dec 2016
Atreya Chloe E, Greene Claire, McWhirter Ryan M, Ikram Nabia S, Allen I Elaine, Van Loon Katherine, Venook Alan P, Yeh Benjamin M, Behr Spencer C
Abstract excerpt
BACKGROUND: BRAF-mutant metastatic colorectal cancers (mCRCs) share many clinicopathologic features with right-sided colon tumors, including frequent peritoneal involvement. Because of the poorer outcomes associated with BRAF mutations, early enrollment in clinical trials has been encouraged. However, the use of standard eligibility and assessment criteria, such as measurable disease, has anecdotally impeded...
Topics
- Adult
- Aged
- Aged, 80 and over
- Ascites
- Biomarkers, Tumor
- Colorectal Neoplasms
- Female
- Humans
- Incidence
- Kaplan-Meier Estimate
- Liver Neoplasms
