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Long noncoding RNAs: pivotal regulators in acute myeloid leukemia

1 Dec 2015

Abstract excerpt

Long noncoding RNAs (lncRNAs) have emerged as a class of pivotal regulators of gene expression. Recent studies have shown that lncRNAs contribute to the initiation, maintenance, and development of acute myeloid leukemia (AML). In this review, we summarize the current knowledge of the lncRNAs that play critical roles in AML. We first briefly describe the characteristics of lncRNAs, and then focus on their...

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PMID: 27999732
DOI: 10.1186/s40164-016-0059-9

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