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Article

Intergenic variants may predispose to major depression disorder through regulation of long non-coding RNA expression.

Gene - 15 Feb 2017

Ye Ning, Rao Shuquan, Du Tingfu, Hu Huiling, Liu Zeyue, Shen Yan, Xu Qi

Abstract excerpt

Genome-wide association (GWA) studies have identified numerous genetic variants for major depressive disorder (MDD) although most of the genetic variants are intergenic. It has been found that approximately 54% of long non-coding RNAs (lncRNAs) are located in the intergenic regions. We hypothesized that intergenic variants might be involved in the pathogenesis of MDD through regulating the expression of lncRNAs...

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Identifiers

PMID: 27940106
DOI: 10.1016/j.gene.2016.11.041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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