Article
Unlocking bat immunology: establishment of Pteropus alecto bone marrow-derived dendritic cells and macrophages.
Scientific reports - 9 Dec 2016
Zhou Peng, Chionh Yok Teng, Irac Sergio Erdal, Ahn Matae, Jia Ng Justin Han, Fossum Even, Bogen Bjarne, Ginhoux Florent, Irving Aaron T, Dutertre Charles-Antoine, Wang Lin-Fa
Abstract excerpt
Bats carry and shed many emerging infectious disease agents including Ebola virus and SARS-like Coronaviruses, yet they rarely display clinical symptoms of infection. Bat epithelial or fibroblast cell lines were previously established to study the bat immune response against viral infection. However, the lack of professional immune cells such as dendritic cells (DC) and macrophages has greatly limited the...
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