Article
Phenotypic and functional characterization of the major lymphocyte populations in the fruit-eating bat Pteropus alecto.
Scientific reports - 24 Nov 2016
Martínez Gómez Julia María, Periasamy Pravin, Dutertre Charles-Antoine, Irving Aaron Trent, Ng Justin Han Jia, Crameri Gary, Baker Michelle L, Ginhoux Florent, Wang Lin-Fa, Alonso Sylvie
Abstract excerpt
The unique ability of bats to act as reservoir for viruses that are highly pathogenic to humans suggests unique properties and functional characteristics of their immune system. However, the lack of bat specific reagents, in particular antibodies, has limited our knowledge of bat's immunity. Using cross-reactive antibodies, we report the phenotypic and functional characterization of T cell subsets, B and NK cells...
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