Article
Genomic Control of Retinal Cell Number: Challenges, Protocol, and Results.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017
Keeley Patrick W, Whitney Irene E, Reese Benjamin E
Abstract excerpt
This chapter considers some of the challenges in obtaining accurate and consistent estimates of neuronal population size in the mouse retina, in order to identify the genetic control of cell number through QTL mapping and candidate gene analysis. We first discuss a variety of best practices for analyzing large numbers of recombinant inbred strains of mice over the course of a year in order to amass a satisfactory...
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