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Article

Genetic Variation in One-Carbon Metabolism and Changes in Metabolic Parameters in First-Episode Schizophrenia Patients.

The international journal of neuropsychopharmacology - 1 Mar 2017

Misiak Blazej, Laczmanski Lukasz, Sloka Natalia Kinga, Szmida Elzbieta, Slezak Ryszard, Piotrowski Patryk, Kiejna Andrzej, Frydecka Dorota

Abstract excerpt

Background: In this study, we aimed to investigate the effects of polymorphisms in genes encoding 1-carbon metabolism enzymes on differential development of metabolic parameters during 12 weeks of treatment with second-generation antipsychotics in first-episode schizophrenia patients. Methods: The following polymorphisms in 1-carbon metabolism genes were genotyped: MTHFR (C677T and A1298C), MTHFD1 (G1958A), MTRR...

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Source

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Identifiers

PMID: 27932499
DOI: 10.1093/ijnp/pyw094
PMCID: PMC5408968

Genes

MTHFR
BHMT
MTHFD1
MTRR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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