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EMT Regulation by Autophagy: A New Perspective in Glioblastoma Biology

6 Mar 2019

Abstract excerpt

Epithelial-to-mesenchymal transition (EMT) and its reverse process MET naturally occur during development and in tissue repair in vertebrates. EMT is also recognized as the crucial event by which cancer cells acquire an invasive phenotype through the activation of specific transcription factors and signalling pathways. Even though glial cells have a mesenchymal phenotype, an EMT-like process tends to exacerbate...

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PMID: 30845654
DOI: 10.3390/cancers11030312

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