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Article

Cannabis use and risk of schizophrenia: a Mendelian randomization study.

Molecular psychiatry - 1 May 2018

Vaucher J, Keating B J, Lasserre A M, Gan W, Lyall D M, Ward J, Smith D J, Pell J P, Sattar N, Paré G, Holmes M V

Abstract excerpt

Cannabis use is observationally associated with an increased risk of schizophrenia, but whether the relationship is causal is not known. Using a genetic approach, we took 10 independent genetic variants previously identified to associate with cannabis use in 32 330 individuals to determine the nature of the association between cannabis use and risk of schizophrenia. Genetic variants were employed as instruments...

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Identifiers

PMID: 28115737
DOI: 10.1038/mp.2016.252
PMCID: PMC5984096

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