Article
Diverse specificity of cellulosome attachment to the bacterial cell surface.
Scientific reports - 7 Dec 2016
Brás Joana L A, Pinheiro Benedita A, Cameron Kate, Cuskin Fiona, Viegas Aldino, Najmudin Shabir, Bule Pedro, Pires Virginia M R, Romão Maria João, Bayer Edward A, Spencer Holly L, Smith Steven, Gilbert Harry J, Alves Victor D, Carvalho Ana Luísa, Fontes Carlos M G A
Abstract excerpt
During the course of evolution, the cellulosome, one of Nature's most intricate multi-enzyme complexes, has been continuously fine-tuned to efficiently deconstruct recalcitrant carbohydrates. To facilitate the uptake of released sugars, anaerobic bacteria use highly ordered protein-protein interactions to recruit these nanomachines to the cell surface. Dockerin modules located within a non-catalytic...
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