Article
The genetic architecture of the MHC class II region in British Texel sheep.
Immunogenetics - 1 Mar 2017
Ali Alsagher O A, Stear Abigail, Fairlie-Clarke Karen, Brujeni Gholamreza Nikbakht, Isa N Mahiza Md, Salisi M Shahrom Bin, Donskow-Łysoniewska Katarzyna, Groth David, Buitkamp Johannes, Stear Michael J
Abstract excerpt
Understanding the structure of the major histocompatibility complex, especially the number and frequency of alleles, loci and haplotypes, is crucial for efficient investigation of the way in which the MHC influences susceptibility to disease. Nematode infection is one of the most important diseases suffered by sheep, and the class II region has been repeatedly associated with differences in susceptibility and...
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