Article
GATA-3-specific DNAzyme - A novel approach for stratified asthma therapy.
European journal of immunology - 1 Jan 2017
Garn Holger, Renz Harald
Abstract excerpt
It is now well established that type-2 immune mechanisms drive the inflammation in about 50% of asthma patients. The major cellular and molecular players regulating this important network have been identified. In terms of therapeutic intervention, cytokine and cytokine-receptor pathways have been given major attention, since these molecules are relatively easily accessible for a blockade through monoclonal...
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