Article
DISCO Interacting Protein 2 regulates axonal bifurcation and guidance of Drosophila mushroom body neurons.
Developmental biology - 15 Jan 2017
Nitta Yohei, Yamazaki Daisuke, Sugie Atsushi, Hiroi Makoto, Tabata Tetsuya
Abstract excerpt
Axonal branching is one of the key processes within the enormous complexity of the nervous system to enable a single neuron to send information to multiple targets. However, the molecular mechanisms that control branch formation are poorly understood. In particular, previous studies have rarely addressed the mechanisms underlying axonal bifurcation, in which axons form new branches via splitting of the growth...
Topics
- Animals
- Animals, Genetically Modified
- Axon Guidance
- Axons
- Clone Cells
- Drosophila Proteins
- Drosophila melanogaster
- Fatty Acids
- Lipid Metabolism
- Models, Biological
- Mushroom Bodies
- Mutation
- Nerve Tissue Proteins
- Protein Domains
- RNA Interference
- Sequence Deletion
- Sequence Homology, Amino Acid