Article
The 5΄ UTR of the type I toxin ZorO can both inhibit and enhance translation.
Nucleic acids research - 20 Apr 2017
Wen Jia, Harp John R, Fozo Elizabeth M
Abstract excerpt
Many bacterial type I toxin mRNAs possess a long 5΄ untranslated region (UTR) that serves as the target site of the corresponding antitoxin sRNA. This is the case for the zorO-orzO type I system where the OrzO antitoxin base pairs to the 174-nucleotide zorO 5΄ UTR. Here, we demonstrate that the full-length 5΄ UTR of the zorO type I toxin hinders its own translation independent of the sRNA whereas a processed 5΄...
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