Article
In silico analysis of surface structure variation of PCV2 capsid resulting from loop mutations of its capsid protein (Cap).
The Journal of general virology - 1 Dec 2016
Wang Naidong, Zhan Yang, Wang Aibing, Zhang Lijie, Khayat Reza, Yang Yi
Abstract excerpt
Outbreaks of porcine circovirus (PCV) type 2 (PCV2)-associated diseases have caused substantial economic losses worldwide in the last 20 years. The PCV capsid protein (Cap) is the sole structural protein and main antigenic determinant of this virus. In this study, not only were phylogenetic trees reconstructed, but variations of surface structure of the PCV capsid were analysed in the course of evolution. Unique...
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