Article
Fine mapping of antigenic epitopes on capsid proteins of porcine circovirus, and antigenic phenotype of porcine circovirus type 2.
Molecular immunology - 1 Jan 2009
Shang Shao-Bin, Jin Yu-Lan, Jiang Xue-tao, Zhou Ji-Yong, Zhang Xin, Xing Gang, He Jia Ling, Yan Yan
Abstract excerpt
Type 2 porcine circovirus (PCV2) is associated with post-weaning multisystemic wasting syndrome in pigs. In this study, three monoclonal antibodies (mAbs) against the capsid protein (Cap) of PCV2, eight mAbs to Cap of type 1 porcine circovirus (PCV1) and five mAbs specific for Cap of both PCV1 and PCV2, were generated and used to finely map the antigenic sites of PCV1 and PCV2, and to identify the antigenic...
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