Article
Evolutionary changes in the capsid P2 region of Australian strains of the norovirus GII.Pe_GII.4.
Journal of medical microbiology - 1 Jul 2017
Bruggink Leesa D, Moselen Jean M, Roberts Jason A, Marshall John A
Abstract excerpt
PURPOSE: The protruding (P) 2 region of the norovirus capsid is thought to include hypervariable sites involved in receptor binding. This study examines the changes that occurred in the P2 region of GII.Pe_GII.4 norovirus in the course of its evolution from a precursor phase (2008-2009), to an intermediate phase (2010) and finally to an epidemic phase (2012-2015). METHODOLOGY: Twenty-two P2 region amino acid (aa)...
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