Article
Genotype-based dosing algorithms for warfarin therapy: data review and recommendations.
Molecular diagnosis & therapy - 1 Oct 2011
Johnson Eric G, Horne Benjamin D, Carlquist John F, Anderson Jeffrey L
Abstract excerpt
Warfarin, the most common oral anticoagulant, is the ideal candidate for pharmacogenetic dosing and gene-based 'individualization' of care. A plethora of studies have shown that stable dose requirements can be predicted using sequence variants in the CYP2C9 and VKORC1 genes in both sexes and in d...
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