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Article

Prospective Evaluation of the Utility of Whole Exome Sequencing in Dilated Cardiomyopathy.

Journal of the American Heart Association - 21 Jan 2020

Ramchand Jay, Wallis Mathew, Macciocca Ivan, Lynch Elly, Farouque Omar, Martyn Melissa, Phelan Dean, Chong Belinda, Lockwood Siobhan, Weintraub Robert, Thompson Tina, Trainer Alison, Zentner Dominica, Vohra Jitendra, Chetrit Michael, Hare David L, James Paul

Abstract excerpt

Background Dilated cardiomyopathy may be heritable but shows extensive genetic heterogeneity. The utility of whole exome sequencing as a first-line genetic test for patients with dilated cardiomyopathy in a contemporary "real-world" setting has not been specifically established. Using whole exome sequencing with rigorous, evidence-based variant interpretation, we aimed to identify the prevalence of a molecular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31931689
DOI: 10.1161/JAHA.119.013346
PMCID: PMC7033851

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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