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Exploring the impact of EGFR T790M neighboring SNPs on ARMS-based T790M mutation assay

26 Sept 2016

Abstract excerpt

The present study aimed to explore the influence of T790M neighboring single nucleotide polymorphism (SNP) on the sensitivity of amplification refractory mutation system (ARMS)‑based T790M mutation assay. Three ARMS‑quantitative polymerase chain reaction (qPCR) systems (system 1 had a forward ARMS primer without rs1050171, system 2 included a forward ARMS primer with rs1050171 and system 3 contained the above two...

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PMID: 27895798
DOI: 10.3892/ol.2016.5184

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