Article
Multimodality Imaging Identifies Distinct Metabolic Profiles In Vitro and In Vivo.
Neoplasia (New York, N.Y.) - 1 Dec 2016
Neveu Marie-Aline, De Preter Géraldine, Marchand Valérie, Bol Anne, Brender Jeffery R, Saito Keita, Kishimoto Shun, Porporato Paolo E, Sonveaux Pierre, Grégoire Vincent, Feron Olivier, Jordan Bénédicte F, Krishna Murali C, Gallez Bernard
Abstract excerpt
The study of alterations of tumor metabolism should allow the identification of new targets for innovative anticancer strategies. Metabolic alterations are generally established in vitro, and conclusions are often extrapolated to the in vivo situation without further tumor metabolic phenotyping. To highlight the key role of microenvironment on tumor metabolism, we studied the response of glycolytic and oxidative...
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