Article
Non-heat shock responsive roles of HSF1 in Candida albicans are essential under iron deprivation and drug defense.
Biochimica et biophysica acta. Molecular cell research - 1 Feb 2017
Nair Remya, Shariq Mohd, Dhamgaye Sanjiveeni, Mukhopadhyay Chinmay K, Shaikh Shamim, Prasad Rajendra
Abstract excerpt
Recently, we have reported that the conditional mutant of the heat shock factor-1 (HSF1) in Candida albicans displays enhanced susceptibility not only towards a plant alkaloid, berberine, but also to diverse antifungal drugs. The present study attempts to identify additional phenotypes highlighting the non-heat shock responsive roles of HSF1 that could be correlated with the enhanced drug susceptibility. We...
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