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Article

A visfatin promoter polymorphism is associated with low-grade inflammation and type 2 diabetes.

Obesity (Silver Spring, Md.) - 1 Dec 2006

Zhang Yuan-Yuan, Gottardo Lucia, Thompson Ryan, Powers Christine, Nolan David, Duffy Jill, Marescotti Maria Cristina, Avogaro Angelo, Doria Alessandro

Abstract excerpt

Visfatin (also known as pre-B cell colony-enhancing factor, or PBEF) is a pro-inflammatory adipokine expressed predominantly in visceral fat. We investigated whether polymorphisms at the visfatin/PBEF locus influence the risk of type 2 diabetes (T2D). Linkage disequilibrium analysis of 52 single nucleotide polymorphisms spanning the entire gene (34.7 kb) plus 20.5 kb of the upstream region and 25.5 kb of the...

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Identifiers

PMID: 17189536
DOI: 10.1038/oby.2006.247

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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A visfatin promoter polymorphism is associated with low-grade inflammation and type 2 diabetes.PMID 17189536Read ↗

Association of Visfatin gene polymorphism with obesity related metabolic disorders among Pakistani population: a case control study.Semantic proximity Read ↗

A rare variant in the visfatin gene (NAMPT/PBEF1) is associated with protection from obesity.Semantic proximity Read ↗

The visfatin (PBEF1) G-948T gene polymorphism is associated with increased high-density lipoprotein cholesterol in obese subjects.Semantic proximity Read ↗

Genetic variation in the visfatin gene (PBEF1) and its relation to glucose metabolism and fat-depot-specific messenger ribonucleic acid expression in humans.Semantic proximity Read ↗

The -1535 promoter variant of the visfatin gene is associated with serum triglyceride and HDL-cholesterol levels in Japanese subjects.Semantic proximity Read ↗

Genetic variation in the visfatin (PBEF1/NAMPT) gene and type 2 diabetes in the Greek population.Semantic proximity Read ↗

Effects of genetic variation in the visfatin gene (PBEF1) on obesity, glucose metabolism, and blood pressure in children.Semantic proximity Read ↗

The visfatin gene is associated with glucose and lipid metabolism in a Chinese population.Semantic proximity Read ↗

Visfatin genotype may modify the insulin resistance and lipid profile in type 2 diabetes patients.Semantic proximity Read ↗

Common polymorphisms in the promoter of the visfatin gene (PBEF1) influence plasma insulin levels in a French-Canadian population.Semantic proximity Read ↗

Visfatin: Structure, Function and Relation to Diabetes Mellitus and Other DysfunctionsSemantic proximity Read ↗

Visfatin and its genetic variants are associated with obesity-related morbidities and cardiometabolic risk in severely obese children.Semantic proximity Read ↗

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