Article

Host - Tumor Determinants of Chemotherapy Toxicity and Resistance in the Postoperative Management of Geriatric Colorectal Cancer: A Mechanistic Scoping Review

2026-05-11

Abstract excerpt

<title>Abstract</title> <p> <bold>Purpose</bold> The postoperative management of elderly colorectal cancer (CRC) patients presents a persistent clinical dilemma in which efforts to optimize adjuvant chemotherapy efficacy are constrained by heightened vulnerability to treatment-related toxicity. Reliance on chronological age and body surface area–based dosing fails to account for substantial biological heterogen...

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Literature Corpus work: d0194a2d-993d-54d8-9fea-4ccd6e80e568
DOI: 10.21203/rs.3.rs-9258998/v1

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