Article
Analysis of Viral Epigenotypes Using Chromatin Immunoprecipitation.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017
Bánáti Ferenc, Szenthe Kálmán
Abstract excerpt
Chromatin Immunoprecipitation (ChIP) is a method used to detect DNA-protein interactions in vivo. ChIP has been widely applied to assess the abundance of various epigenetic regulators, including modified histones, in various regions of cellular and viral chromatin. During the procedure, DNA binding proteins are covalently cross-linked to DNA, and the isolated chromatin is broken into pieces of 300-500 bps in...
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