Article
Augmented Th17-type immune responses in preterm neonates exposed to histologic chorioamnionitis.
Pediatric research - 1 Apr 2017
Rito Daniel C, Viehl Luke T, Buchanan Paula M, Haridas Seema, Koenig Joyce M
Abstract excerpt
BACKGROUND: Histologic chorioamnionitis (HCA) is a placental inflammatory disorder that frequently precedes preterm delivery. HCA increases risk for long-standing inflammatory injury and may influence immune programming, particularly in preterm (PT) neonates. We hypothesized that HCA exposure is associated with an increased circulating frequency of proinflammatory, Th17-type responses. METHODS: Placental cord...
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