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Clinical, Genetic and Innate Immunity Characteristics of Melanoma in Organ Transplant Recipients.

Acta dermato-venereologica - 6 Apr 2017

Brocard Anabelle, Knol Anne-Chantal, Bossard Céline, Denis Marc Guillaume, Quéreux Gaëlle, Saint-Jean Mélanie, Peuvrel Lucie, Khammari Amir, Blancho Gilles, Dantal Jacques, Dréno Brigitte

Abstract excerpt

The aims of this study were to determine the clinical and histological characteristics of melanoma in transplant recipients, the mutation profile (BRAF, NRAS and c-KIT genes), and the immune tolerance of the tumour microenvironment by immunohistochemical study of the expression of indoleamine 2,3-dioxygenase (IDO), PD1, PD-L1, CD8 and FoxP3. The study population comprised patients who had undergone a renal...

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Source

Identifiers

PMID: 27868139
DOI: 10.2340/00015555-2568

Genes

BRAF
KIT
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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