Article
BRAF mutations in melanocytic tumors (nevi and melanomas) from organ transplant recipients.
European journal of dermatology : EJD - 1 Jan 2000
Kanitakis Jean, Baldassini Sylvie, Lora Viviana, Euvrard Sylvie
Abstract excerpt
BRAF is a gene of the RAF family of kinases, frequently mutated in benign and malignant melanocytic tumors (nevi and melanomas). Organ transplant recipients are at high risk for developing various tumors, including melanocytic ones. We studied a group of 129 melanocytic tumors including various subtypes of nevi (n: 114) and melanomas (n: 15) excised from transplant (n: 63) and control (non-immunosuppressed)...
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