Article
TP53 and 53BP1 Reunited.
Trends in cell biology - 1 May 2017
Soussi Thierry, Kroemer Guido
Abstract excerpt
Identified as a TP53-binding protein, 53BP1 is a key regulator of the cellular response to double-strand breaks, a TP53-independent activity. Recent data have established a new TP53-dependent function for 53BP1 in mitotic surveillance after centrosome loss.
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