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Article

Evaluation of the genetic basis of primary hypoadrenocorticism in Standard Poodles using SNP array genotyping and whole-genome sequencing.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Feb 2017

Friedenberg Steven G, Lunn Katharine F, Meurs Kathryn M

Abstract excerpt

Primary hypoadrenocorticism, also known as Addison's disease, is an autoimmune disorder leading to the destruction of the adrenal cortex and subsequent loss of glucocorticoid and mineralocorticoid hormones. The disease is prevalent in Standard Poodles and is believed to be highly heritable in the breed. Using genotypes derived from the Illumina Canine HD SNP array, we performed a genome-wide association study of...

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Identifiers

PMID: 27864587
DOI: 10.1007/s00335-016-9671-6
PMCID: PMC5495560

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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