Article
Frequency and distribution of 152 genetic disease variants in over 100,000 mixed breed and purebred dogs.
PLoS genetics - 1 Apr 2018
Donner Jonas, Anderson Heidi, Davison Stephen, Hughes Angela M, Bouirmane Julia, Lindqvist Johan, Lytle Katherine M, Ganesan Balasubramanian, Ottka Claudia, Ruotanen Päivi, Kaukonen Maria, Forman Oliver P, Fretwell Neale, Cole Cynthia A, Lohi Hannes
Abstract excerpt
Knowledge on the genetic epidemiology of disorders in the dog population has implications for both veterinary medicine and sustainable breeding. Limited data on frequencies of genetic disease variants across breeds exists, and the disease heritage of mixed breed dogs remains poorly explored to date. Advances in genetic screening technologies now enable comprehensive investigations of the canine disease heritage,...
Topics
- Animals
- Breeding
- Databases, Genetic
- Dog Diseases
- Dogs
- Female
- Gene Frequency
- Genes, Recessive
- Genetic Predisposition to Disease
- Genetic Testing