Article
Reduced angiogenic gene expression in morbillivirus-triggered oncolysis in a translational model for histiocytic sarcoma.
Journal of cellular and molecular medicine - 1 Apr 2017
Pfankuche Vanessa Maria, Spitzbarth Ingo, Lapp Stefanie, Ulrich Reiner, Deschl Ulrich, Kalkuhl Arno, Baumgärtner Wolfgang, Puff Christina
Abstract excerpt
Histiocytic sarcoma represents a rare malignant tumour with a short survival time, indicating the need of novel treatment strategies including oncolytic virotherapy. The underlying molecular mechanisms of viral oncolysis are largely unknown. As cancer in companion animals shares striking similarities with human counterparts, we chose a permanent canine histiocytic sarcoma cell line (DH82 cells) to identify global...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
