Article
Genome-wide gene expression and RNA half-life measurements allow predictions of regulation and metabolic behavior in Methanosarcina acetivorans.
BMC genomics - 16 Nov 2016
Peterson Joseph R, Thor ShengShee, Kohler Lars, Kohler Petra R A, Metcalf William W, Luthey-Schulten Zaida
Abstract excerpt
BACKGROUND: While a few studies on the variations in mRNA expression and half-lives measured under different growth conditions have been used to predict patterns of regulation in bacterial organisms, the extent to which this information can also play a role in defining metabolic phenotypes has yet to be examined systematically. Here we present the first comprehensive study for a model methanogen. RESULTS: We use...
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