Article
Alpha B-Crystallin Protects Rat Articular Chondrocytes against Casein Kinase II Inhibition-Induced Apoptosis.
PloS one - 1 Jan 2016
Lee Sung Won, Rho Jee Hyun, Lee Sang Yeob, Yoo Seung Hee, Kim Hye Young, Chung Won Tae, Yoo Young Hyun
Abstract excerpt
Although alpha (α)B-crystallin is expressed in articular chondrocytes, little is known about its role in these cells. Protein kinase casein kinase 2 (CK2) inhibition induces articular chondrocyte death. The present study examines whether αB-crystallin exerts anti-apoptotic activity in articular chondrocytes. Primary rat articular chondrocytes were isolated from knee joint slices. Cells were treated with CK2...
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