Article
The RNA-binding protein CsrA plays a central role in positively regulating virulence factors in Erwinia amylovora.
Scientific reports - 15 Nov 2016
Ancona Veronica, Lee Jae Hoon, Zhao Youfu
Abstract excerpt
The GacS/GacA two-component system (also called GrrS/GrrA) is a global regulatory system which is highly conserved among gamma-proteobacteria. This system positively regulates non-coding small regulatory RNA csrB, which in turn binds to the RNA-binding protein CsrA. However, how GacS/GacA-Csr system regulates virulence traits in E. amylovora remains unknown. Results from mutant characterization showed that the...
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