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Article

Additive effects of oxytocin receptor gene polymorphisms on reward circuitry in youth with autism.

Molecular psychiatry - 1 Aug 2017

Hernandez L M, Krasileva K, Green S A, Sherman L E, Ponting C, McCarron R, Lowe J K, Geschwind D H, Bookheimer S Y, Dapretto M

Abstract excerpt

Several common alleles in the oxytocin receptor gene (OXTR) are associated with altered brain function in reward circuitry in neurotypical adults and may increase risk for autism spectrum disorders (ASD). Yet, it is currently unknown how variation in the OXTR relates to brain functioning in individuals with ASD, and, critically, whether neural endophenotypes vary as a function of aggregate genetic risk. Here, for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27843152
DOI: 10.1038/mp.2016.209
PMCID: PMC5991611

Genes

OXTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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